Durham (NC) staycation hotels

North America · United States

Your Durham (NC) Staycation

Hand-picked hotels in Durham (NC) — ranked by real guest scores, with live Agoda rates and one-tap booking. From boutique hideaways to luxury icons, every stay is curated by Staycation.

54
Curated stays
8.4/ 10
Average guest score

54 properties · curated by Staycation

Aloft by Marriott Durham DowntownHotel
Durham (NC), United States
Aloft by Marriott Durham Downtown
★★★
9.7Exceptional
For your dates
$389 USD
Unscripted DurhamHotel
Durham (NC), United States
Unscripted Durham
★★★★
8.2Excellent
For your dates
$359 USD
Washington Duke Inn & Golf ClubHotel
Durham (NC), United States
Washington Duke Inn & Golf Club
★★★★
9.5Exceptional
For your dates
$335 USD
21c Museum Hotel DurhamHotel
Durham (NC), United States
21c Museum Hotel Durham
★★★★
8.7Excellent
For your dates
$329 USD
Delta Hotels by Marriott Raleigh-Durham at Research Triangle ParkHotel
Durham (NC), United States
Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park
★★★★
9.2Exceptional
For your dates
$297 USD
JB Duke HotelHotel
Durham (NC), United States
JB Duke Hotel
★★★★
8.4Excellent
For your dates
$270 USD
Hilton Garden Inn Durham/University Medical CenterHotel
Durham (NC), United States
Hilton Garden Inn Durham/University Medical Center
★★★
8.8Excellent
For your dates
$245 USD
SpringHill Suites by Marriott Durham City ViewHotel
Durham (NC), United States
SpringHill Suites by Marriott Durham City View
★★★★
8.4Excellent
For your dates
$232 USD
AC Hotel DurhamHotel
Durham (NC), United States
AC Hotel Durham
★★★
9.2Exceptional
For your dates
$210 USD
Residence Inn by Marriott Durham McPherson/Duke University Medical Center AreaHotel
Durham (NC), United States
Residence Inn by Marriott Durham McPherson/Duke University Medical Center Area
★★★
5.6Good
For your dates
$210 USD
DoubleTree Suites by Hilton Raleigh - DurhamHotel
Durham (NC), United States
DoubleTree Suites by Hilton Raleigh - Durham
★★★
8.9Excellent
For your dates
$190 USD
Hampton Inn & Suites Durham/North I-85Hotel
Durham (NC), United States
Hampton Inn & Suites Durham/North I-85
★★★
9.2Exceptional
For your dates
$187 USD
Holiday Inn Express Durham By IHGHotel
Durham (NC), United States
Holiday Inn Express Durham By IHG
★★★
9.4Exceptional
For your dates
$157 USD
Holiday Inn Express Chapel Hill By IHGHotel
Durham (NC), United States
Holiday Inn Express Chapel Hill By IHG
★★★
8.6Excellent
For your dates
$154 USD
Fairfield by Marriott Inn & Suites Durham SouthpointHotel
Durham (NC), United States
Fairfield by Marriott Inn & Suites Durham Southpoint
★★★
8.4Excellent
For your dates
$152 USD
Fairfield by Marriott Inn & Suites DurhamHotel
Durham (NC), United States
Fairfield by Marriott Inn & Suites Durham
★★★
7.9Very Good
For your dates
$152 USD
Hilton Durham Near Duke UniversityHotel
Durham (NC), United States
Hilton Durham Near Duke University
★★★
8.4Excellent
For your dates
$149 USD
SpringHill Suites by Marriott Durham Chapel HillHotel
Durham (NC), United States
SpringHill Suites by Marriott Durham Chapel Hill
★★★
9.4Exceptional
For your dates
$146 USD
Hampton Inn & Suites Durham University Medical CenterHotel
Durham (NC), United States
Hampton Inn & Suites Durham University Medical Center
★★★
9.8Exceptional
For your dates
$145 USD
Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle ParkHotel
Durham (NC), United States
Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle Park
★★★★
9.7Exceptional
For your dates
$142 USD
Holiday Inn Express Hotel & Suites Research Triangle Park By IHGHotel
Durham (NC), United States
Holiday Inn Express Hotel & Suites Research Triangle Park By IHG
★★★
8.7Excellent
For your dates
$140 USD
Staybridge Suites Of Durham - Chapel Hill - RTP By IHGHotel
Durham (NC), United States
Staybridge Suites Of Durham - Chapel Hill - RTP By IHG
★★★
9.2Exceptional
For your dates
$139 USD
Homewood Suites by Hilton Durham - Chapel Hill I-40 & Hwy. 15-501Hotel
Durham (NC), United States
Homewood Suites by Hilton Durham - Chapel Hill I-40 & Hwy. 15-501
★★★
9.3Exceptional
For your dates
$130 USD
Home2 Suites by Hilton Durham Chapel HillHotel
Durham (NC), United States
Home2 Suites by Hilton Durham Chapel Hill
★★★
9.0Exceptional
For your dates
$130 USD
Hampton Inn & Suites Chapel Hill/DurhamHotel
Durham (NC), United States
Hampton Inn & Suites Chapel Hill/Durham
★★★
8.6Excellent
For your dates
$123 USD
DoubleTree by Hilton Raleigh - Durham Airport at Research Triangle ParkHotel
Durham (NC), United States
DoubleTree by Hilton Raleigh - Durham Airport at Research Triangle Park
★★★★
9.0Exceptional
For your dates
$122 USD
SpringHill Suites by Marriott Raleigh-Durham Airport/Research Triangle ParkHotel
Durham (NC), United States
SpringHill Suites by Marriott Raleigh-Durham Airport/Research Triangle Park
★★★
8.0Excellent
For your dates
$122 USD
Millennium Hotel DurhamHotel
Durham (NC), United States
Millennium Hotel Durham
★★★
7.8Very Good
For your dates
$120 USD
Homewood Suites by Hilton Raleigh - Durham AP/Research TriangleHotel
Durham (NC), United States
Homewood Suites by Hilton Raleigh - Durham AP/Research Triangle
★★★
8.6Excellent
For your dates
$118 USD
Courtyard by Marriott Durham Near Duke University/DowntownHotel
Durham (NC), United States
Courtyard by Marriott Durham Near Duke University/Downtown
★★★
8.6Excellent
For your dates
$114 USD
Clarion Pointe Durham Research Triangle ParkHotel
Durham (NC), United States
Clarion Pointe Durham Research Triangle Park
★★★
8.3Excellent
For your dates
$113 USD
Comfort Inn University Durham - Chapel HillHotel
Durham (NC), United States
Comfort Inn University Durham - Chapel Hill
★★★
8.2Excellent
For your dates
$113 USD
La Quinta Inn & Suites by Wyndham Univ Area Chapel HillHotel
Durham (NC), United States
La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill
★★★
8.4Excellent
For your dates
$110 USD
Hilton Garden Inn Durham SouthpointHotel
Durham (NC), United States
Hilton Garden Inn Durham Southpoint
★★★
8.4Excellent
For your dates
$107 USD
Comfort Inn & Suites Durham near Duke UniversityHotel
Durham (NC), United States
Comfort Inn & Suites Durham near Duke University
★★★
8.9Excellent
For your dates
$105 USD
Hilton Garden Inn Raleigh-Durham/Research Triangle ParkHotel
Durham (NC), United States
Hilton Garden Inn Raleigh-Durham/Research Triangle Park
★★★
9.5Exceptional
For your dates
$99 USD
Extended Stay America Select Suites - Durham - UniversityHotel
Durham (NC), United States
Extended Stay America Select Suites - Durham - University
★★
8.5Excellent
For your dates
$95 USD
Extended Stay America Suites - Raleigh - RTP - 4919 Miami Blvd.Hotel
Durham (NC), United States
Extended Stay America Suites - Raleigh - RTP - 4919 Miami Blvd.
★★★
7.3Very Good
For your dates
$94 USD
Sonesta Select Durham Research Triangle ParkHotel
Durham (NC), United States
Sonesta Select Durham Research Triangle Park
★★★
8.2Excellent
For your dates
$93 USD
Wingate by Wyndham Raleigh Durham / AirportHotel
Durham (NC), United States
Wingate by Wyndham Raleigh Durham / Airport
★★★
8.1Excellent
For your dates
$91 USD
Candlewood Suites Durham By IHGHotel
Durham (NC), United States
Candlewood Suites Durham By IHG
★★★
8.0Excellent
For your dates
$89 USD
Extended Stay America Select Suites - Raleigh - RTP - 4610 Miami Blvd.Hotel
Durham (NC), United States
Extended Stay America Select Suites - Raleigh - RTP - 4610 Miami Blvd.
★★★
8.5Excellent
For your dates
$88 USD
Sleep Inn Raleigh Durham AirportHotel
Durham (NC), United States
Sleep Inn Raleigh Durham Airport
★★★
7.3Very Good
For your dates
$85 USD
La Quinta Inn & Suites by Wyndham Raleigh/Durham SouthpointHotel
Durham (NC), United States
La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint
★★★
6.9Good
For your dates
$83 USD
Red Roof Inn Durham - Duke Univ Medical CenterHotel
Durham (NC), United States
Red Roof Inn Durham - Duke Univ Medical Center
★★
7.4Very Good
For your dates
$78 USD
Red Roof Inn Durham - Triangle ParkHotel
Durham (NC), United States
Red Roof Inn Durham - Triangle Park
★★
7.2Very Good
For your dates
$74 USD
SureStay Plus by Best Western Durham Medical CenterHotel
Durham (NC), United States
SureStay Plus by Best Western Durham Medical Center
7.1Very Good
For your dates
$65 USD
Suburban Studios Durham-RaleighHotel
Durham (NC), United States
Suburban Studios Durham-Raleigh
★★
4.8Good
For your dates
$63 USD
Econo Lodge Research Triangle ParkHotel
Durham (NC), United States
Econo Lodge Research Triangle Park
★★
7.9Very Good
For your dates
$61 USD
OYO Hotel Durham West HillsHotel−20%
Durham (NC), United States
OYO Hotel Durham West Hills
★★★
7.7Very Good
For your dates
$50 USD
$65 USD
Home2 Suites by Hilton Durham University Medical CenterHotel
Durham (NC), United States
Home2 Suites by Hilton Durham University Medical Center
★★★
10.0Exceptional
Durham Marriott City CenterHotel
Durham (NC), United States
Durham Marriott City Center
★★★★
8.8Excellent
Marriott Raleigh Durham Research Triangle ParkHotel
Durham (NC), United States
Marriott Raleigh Durham Research Triangle Park
★★★★
7.7Very Good
Super 8 By Wyndham Durham/University Area NcHotel
Durham (NC), United States
Super 8 By Wyndham Durham/University Area Nc
★★
6.8Good

The Best Durham (NC) Staycation Hotels

Whether you’re planning a weekend staycation in Durham (NC) or a longer escape acrossUnited States, Staycation curates the finest places to stay — from boutique hideaways and heritage hotels to iconic luxury properties. Every Durham (NC) staycation hotel is ranked by real guest scores, so you can book with confidence.

Rates are powered by Agoda, with live availability and competitive pricing. Pick your dates above to see tonight’s best Durham (NC) staycation deals, or explore other destinations in North America.