Panama City staycation hotels

Central America and Caribbean · Panama

Your Panama City Staycation

Hand-picked hotels in Panama City — ranked by real guest scores, with live Agoda rates and one-tap booking. From boutique hideaways to luxury icons, every stay is curated by Staycation.

60
Curated stays
8.7/ 10
Average guest score
9
5-star properties

60 properties · curated by Staycation

Sofitel Legend Casco ViejoHotel
Panama City, Panama
Sofitel Legend Casco Viejo
★★★★★
9.5Exceptional
For your dates
$365 USD
JW Marriott PanamaHotel
Panama City, Panama
JW Marriott Panama
★★★★★
8.3Excellent
For your dates
$287 USD
Intercontinental Miramar Panama By IHGHotel
Panama City, Panama
Intercontinental Miramar Panama By IHG
★★★★
8.9Excellent
For your dates
$278 USD
Waldorf Astoria PanamaHotel
Panama City, Panama
Waldorf Astoria Panama
★★★★★
9.1Exceptional
For your dates
$271 USD
Hilton PanamaHotel
Panama City, Panama
Hilton Panama
★★★★
9.1Exceptional
For your dates
$268 USD
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama CityHotel
Panama City, Panama
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City
★★★★★
8.7Excellent
For your dates
$262 USD
W PanamaHotel
Panama City, Panama
W Panama
★★★★★
8.3Excellent
For your dates
$249 USD
The Westin PanamaHotel
Panama City, Panama
The Westin Panama
★★★★
9.5Exceptional
For your dates
$231 USD
La Concordia Boutique HotelHotel
Panama City, Panama
La Concordia Boutique Hotel
★★★★
9.7Exceptional
For your dates
$209 USD
Sortis Hotel, Spa & Casino, Autograph CollectionHotel
Panama City, Panama
Sortis Hotel, Spa & Casino, Autograph Collection
★★★★★
8.5Excellent
For your dates
$209 USD
The Westin Playa Bonita PanamaHotel
Panama City, Panama
The Westin Playa Bonita Panama
★★★★★
8.8Excellent
For your dates
$202 USD
Residence Inn by Marriott Panama CityHotel
Panama City, Panama
Residence Inn by Marriott Panama City
★★★
8.0Excellent
For your dates
$178 USD
Bristol Panama, a Registry Collection HotelHotel
Panama City, Panama
Bristol Panama, a Registry Collection Hotel
★★★★★
9.2Exceptional
For your dates
$169 USD
Marriott Panama HotelHotel
Panama City, Panama
Marriott Panama Hotel
★★★★
9.0Exceptional
For your dates
$169 USD
Central Hotel PanamaHotel
Panama City, Panama
Central Hotel Panama
★★★★
9.0Exceptional
For your dates
$168 USD
Le Méridien PanamaHotel
Panama City, Panama
Le Méridien Panama
★★★★
8.6Excellent
For your dates
$167 USD
Riu Plaza PanamaHotel
Panama City, Panama
Riu Plaza Panama
★★★★★
8.9Excellent
For your dates
$147 USD
$589 USD
Tantalo Hotel - Kitchen - RoofbarHotel
Panama City, Panama
Tantalo Hotel - Kitchen - Roofbar
★★★★
8.8Excellent
For your dates
$146 USD
Courtyard by Marriott Panama Multiplaza MallHotel
Panama City, Panama
Courtyard by Marriott Panama Multiplaza Mall
★★★★
8.7Excellent
For your dates
$139 USD
Sheraton Grand PanamaHotel
Panama City, Panama
Sheraton Grand Panama
★★★★
7.9Very Good
For your dates
$134 USD
Renaissance Panama City HotelHotel
Panama City, Panama
Renaissance Panama City Hotel
★★★★★
8.8Excellent
For your dates
$127 USD
Courtyard by Marriott Panama MetromallHotel
Panama City, Panama
Courtyard by Marriott Panama Metromall
★★★★
8.4Excellent
For your dates
$124 USD
Best Western Plus Panama Zen HotelHotel
Panama City, Panama
Best Western Plus Panama Zen Hotel
8.9Excellent
For your dates
$124 USD
Aloft by Marriott PanamaHotel
Panama City, Panama
Aloft by Marriott Panama
★★★★
8.8Excellent
For your dates
$119 USD
Marriott Executive Apartments Panama City, FinisterreHotel
Panama City, Panama
Marriott Executive Apartments Panama City, Finisterre
★★★★
8.3Excellent
For your dates
$118 USD
Holiday Inn Panama Canal By IHGHotel
Panama City, Panama
Holiday Inn Panama Canal By IHG
★★★
8.1Excellent
For your dates
$114 USD
Holiday Inn Panama Distrito Financiero By IHGHotel
Panama City, Panama
Holiday Inn Panama Distrito Financiero By IHG
★★★★
8.6Excellent
For your dates
$104 USD
HOTEL MIO PANAMAHotel
Panama City, Panama
HOTEL MIO PANAMA
★★★★
8.8Excellent
For your dates
$102 USD
Crowne Plaza Panama By IHGHotel
Panama City, Panama
Crowne Plaza Panama By IHG
★★★★
8.1Excellent
For your dates
$101 USD
Ramada Plaza by Wyndham Panama Punta PacificaHotel
Panama City, Panama
Ramada Plaza by Wyndham Panama Punta Pacifica
★★★★
9.3Exceptional
For your dates
$97 USD
Waymore Hotel Spa & CasinoHotel
Panama City, Panama
Waymore Hotel Spa & Casino
★★★★
9.1Exceptional
For your dates
$95 USD
Hilton Garden Inn Panama City DowntownHotel
Panama City, Panama
Hilton Garden Inn Panama City Downtown
★★★
8.0Excellent
For your dates
$94 USD
Best Western El Dorado Panama HotelHotel
Panama City, Panama
Best Western El Dorado Panama Hotel
8.9Excellent
For your dates
$94 USD
Radisson Decapolis Hotel Panama CityHotel
Panama City, Panama
Radisson Decapolis Hotel Panama City
★★★★
8.5Excellent
For your dates
$93 USD
Torres de Alba Hotel & SuitesHotel
Panama City, Panama
Torres de Alba Hotel & Suites
★★★★
8.8Excellent
For your dates
$91 USD
Plaza Paitilla InnHotel
Panama City, Panama
Plaza Paitilla Inn
★★★★
9.1Exceptional
For your dates
$91 USD
Hotel Casa PanamaHotel−30%
Panama City, Panama
Hotel Casa Panama
★★★★
7.9Very Good
For your dates
$86 USD
$343 USD
TRYP by Wyndham Panama CentroHotel
Panama City, Panama
TRYP by Wyndham Panama Centro
★★★★
8.7Excellent
For your dates
$82 USD
The Executive HotelHotel
Panama City, Panama
The Executive Hotel
★★★★
9.2Exceptional
For your dates
$82 USD
Radisson Hotel Panama CanalHotel
Panama City, Panama
Radisson Hotel Panama Canal
★★★★
8.3Excellent
For your dates
$78 USD
Exe Oriental PanamaHotel
Panama City, Panama
Exe Oriental Panama
★★★★
8.1Excellent
For your dates
$74 USD
Hotel Coral SuitesHotel
Panama City, Panama
Hotel Coral Suites
★★★★
8.5Excellent
For your dates
$68 USD
Hotel Bahia SuitesHotel
Panama City, Panama
Hotel Bahia Suites
★★★★
8.4Excellent
For your dates
$62 USD
Metro Hotel PanamaHotel
Panama City, Panama
Metro Hotel Panama
★★★★
9.0Exceptional
For your dates
$60 USD
Hotel TerranovaHotel
Panama City, Panama
Hotel Terranova
★★★
8.4Excellent
For your dates
$55 USD
Grand International HotelHotel
Panama City, Panama
Grand International Hotel
★★★
8.6Excellent
For your dates
$54 USD
$66 USD
Ramada Panama Centro Via ArgentinaHotel
Panama City, Panama
Ramada Panama Centro Via Argentina
★★★
8.0Excellent
For your dates
$53 USD
Principe Hotel and suitesHotel
Panama City, Panama
Principe Hotel and suites
★★★
8.8Excellent
For your dates
$52 USD
CanovaHotel
Panama City, Panama
Canova
★★★
8.5Excellent
For your dates
$39 USD
EurohotelHotel
Panama City, Panama
Eurohotel
★★★
8.5Excellent
For your dates
$38 USD
Hotel Benidorm PanamaHotel
Panama City, Panama
Hotel Benidorm Panama
★★★
8.2Excellent
For your dates
$36 USD
Residencial & Hotel PalazzoHotel
Panama City, Panama
Residencial & Hotel Palazzo
★★★
9.2Exceptional
For your dates
$32 USD
$40 USD
Hotel LatinoHotel
Panama City, Panama
Hotel Latino
★★★
8.1Excellent
For your dates
$24 USD
Hostel Posada 1914Hotel
Panama City, Panama
Hostel Posada 1914
★★
9.0Exceptional
For your dates
$24 USD
Hotel Plaza HerreraHotel
Panama City, Panama
Hotel Plaza Herrera
★★★★
9.8Exceptional
Global Hotel Panama - Twist Hotels CorpHotel
Panama City, Panama
Global Hotel Panama - Twist Hotels Corp
★★★★
9.1Exceptional
Magnolia InnHotel
Panama City, Panama
Magnolia Inn
★★★
9.0Exceptional
Las ClementinasHotel
Panama City, Panama
Las Clementinas
8.6Excellent
Hyatt Regency Panama CityHotel
Panama City, Panama
Hyatt Regency Panama City
★★★★★
8.4Excellent
Hotel Tower House SuitesHotel
Panama City, Panama
Hotel Tower House Suites
★★★
8.4Excellent

The Best Panama City Staycation Hotels

Whether you’re planning a weekend staycation in Panama City or a longer escape acrossPanama, Staycation curates the finest places to stay — from boutique hideaways and heritage hotels to iconic luxury properties. Every Panama City staycation hotel is ranked by real guest scores, so you can book with confidence.

Rates are powered by Agoda, with live availability and competitive pricing. Pick your dates above to see tonight’s best Panama City staycation deals, or explore other destinations in Central America and Caribbean.