Rochester (MN) staycation hotels

North America · United States

Your Rochester (MN) Staycation

Hand-picked hotels in Rochester (MN) — ranked by real guest scores, with live Agoda rates and one-tap booking. From boutique hideaways to luxury icons, every stay is curated by Staycation.

47
Curated stays
8.3/ 10
Average guest score
1
5-star properties

47 properties · curated by Staycation

Residence Inn by Marriott Rochester Mayo Clinic AreaHotel
Rochester (MN), United States
Residence Inn by Marriott Rochester Mayo Clinic Area
★★★
4.0Good
For your dates
$199 USD
Rochester Marriott Mayo Clinic AreaHotel
Rochester (MN), United States
Rochester Marriott Mayo Clinic Area
★★★★
8.0Excellent
For your dates
$189 USD
Hilton Rochester Mayo Clinic AreaHotel
Rochester (MN), United States
Hilton Rochester Mayo Clinic Area
★★★★
9.3Exceptional
For your dates
$180 USD
Staybridge Suites Rochester - Mayo Clinic Area By IHGHotel
Rochester (MN), United States
Staybridge Suites Rochester - Mayo Clinic Area By IHG
★★★
9.6Exceptional
For your dates
$169 USD
Hyatt House Rochester/mayo ClinicHotel
Rochester (MN), United States
Hyatt House Rochester/mayo Clinic
★★★
8.3Excellent
For your dates
$169 USD
Broadway Plaza, Trademark Collection by WyndhamHotel
Rochester (MN), United States
Broadway Plaza, Trademark Collection by Wyndham
★★★
8.5Excellent
For your dates
$164 USD
Courtyard by Marriott Rochester Mayo Clinic Area/Saint MarysHotel
Rochester (MN), United States
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
★★★
8.5Excellent
For your dates
$161 USD
Home2 Suites by Hilton Rochester Mayo Clinic AreaHotel
Rochester (MN), United States
Home2 Suites by Hilton Rochester Mayo Clinic Area
★★★
9.3Exceptional
For your dates
$152 USD
Holiday Inn Express Rochester South Mayo Area By IHGHotel
Rochester (MN), United States
Holiday Inn Express Rochester South Mayo Area By IHG
★★★
8.4Excellent
For your dates
$149 USD
Homewood Suites by Hilton Rochester Mayo Clinic Area/ Saint MarysHotel
Rochester (MN), United States
Homewood Suites by Hilton Rochester Mayo Clinic Area/ Saint Marys
★★★
8.8Excellent
For your dates
$147 USD
Residence Inn by Marriott Rochester Mayo Clinic Area SouthHotel
Rochester (MN), United States
Residence Inn by Marriott Rochester Mayo Clinic Area South
★★★
9.4Exceptional
For your dates
$142 USD
Kahler Grand HotelHotel
Rochester (MN), United States
Kahler Grand Hotel
★★★
8.1Excellent
For your dates
$136 USD
Holiday Inn Express and Suites Rochester West-Medical Center By IHGHotel
Rochester (MN), United States
Holiday Inn Express and Suites Rochester West-Medical Center By IHG
★★★
9.1Exceptional
For your dates
$135 USD
EVEN Hotel Rochester Mayo Clinic Area by IHGHotel
Rochester (MN), United States
EVEN Hotel Rochester Mayo Clinic Area by IHG
★★★★
9.2Exceptional
For your dates
$132 USD
Hampton Inn & Suites Rochester-NorthHotel
Rochester (MN), United States
Hampton Inn & Suites Rochester-North
★★★
9.5Exceptional
For your dates
$130 USD
TownePlace Suites by Marriott RochesterHotel
Rochester (MN), United States
TownePlace Suites by Marriott Rochester
★★★
0.0Good
For your dates
$130 USD
Fairfield by Marriott Inn & Suites Rochester Mayo Clinic Area/Saint MarysHotel
Rochester (MN), United States
Fairfield by Marriott Inn & Suites Rochester Mayo Clinic Area/Saint Marys
★★★
0.0Good
For your dates
$130 USD
Comfort Inn & Suites West - Medical CenterHotel
Rochester (MN), United States
Comfort Inn & Suites West - Medical Center
★★★
9.4Exceptional
For your dates
$129 USD
TownePlace Suites by Marriott Rochester Mayo Clinic AreaHotel
Rochester (MN), United States
TownePlace Suites by Marriott Rochester Mayo Clinic Area
★★★
7.6Very Good
For your dates
$127 USD
Staybridge Suites Rochester By IHGHotel
Rochester (MN), United States
Staybridge Suites Rochester By IHG
★★★
9.0Exceptional
For your dates
$124 USD
Hilton Garden Inn Rochester DowntownHotel
Rochester (MN), United States
Hilton Garden Inn Rochester Downtown
★★★
8.9Excellent
For your dates
$122 USD
Hotel Indigo Rochester Mayo Clinic Area By IHGHotel
Rochester (MN), United States
Hotel Indigo Rochester Mayo Clinic Area By IHG
★★★
8.9Excellent
For your dates
$120 USD
Kahler Inn and SuitesHotel
Rochester (MN), United States
Kahler Inn and Suites
★★★★
8.1Excellent
For your dates
$118 USD
AmericInn by Wyndham Rochester Near Mayo ClinicHotel
Rochester (MN), United States
AmericInn by Wyndham Rochester Near Mayo Clinic
★★★
6.5Good
For your dates
$109 USD
Centerstone Plaza Hotel Soldiers FieldHotel
Rochester (MN), United States
Centerstone Plaza Hotel Soldiers Field
★★★
9.0Exceptional
For your dates
$107 USD
Sleep Inn & Suites West-Near Medical CenterHotel
Rochester (MN), United States
Sleep Inn & Suites West-Near Medical Center
★★★
9.3Exceptional
For your dates
$106 USD
Candlewood Suites Rochester Mayo Clinic Area By IHGHotel
Rochester (MN), United States
Candlewood Suites Rochester Mayo Clinic Area By IHG
★★★
6.5Good
For your dates
$105 USD
SpringHill Suites by Marriott Rochester Mayo Clinic Area/Saint MarysHotel
Rochester (MN), United States
SpringHill Suites by Marriott Rochester Mayo Clinic Area/Saint Marys
★★★
8.9Excellent
For your dates
$103 USD
Hampton Inn RochesterHotel
Rochester (MN), United States
Hampton Inn Rochester
★★★
9.7Exceptional
For your dates
$103 USD
Best Western Rochester Hotel Mayo Clinic Area/St. Mary'sHotel
Rochester (MN), United States
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
8.6Excellent
For your dates
$101 USD
Quality Inn & Suites Mayo Clinic AreaHotel
Rochester (MN), United States
Quality Inn & Suites Mayo Clinic Area
★★★
9.0Exceptional
For your dates
$99 USD
Comfort Inn & Suites Rochester South Mayo ClinicHotel
Rochester (MN), United States
Comfort Inn & Suites Rochester South Mayo Clinic
★★
8.9Excellent
For your dates
$91 USD
Spark by Hilton Rochester SouthHotel
Rochester (MN), United States
Spark by Hilton Rochester South
★★★
8.7Excellent
For your dates
$91 USD
Econo Lodge Mayo Clinic AreaHotel
Rochester (MN), United States
Econo Lodge Mayo Clinic Area
★★
8.6Excellent
For your dates
$85 USD
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic SHotel
Rochester (MN), United States
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
★★★
8.9Excellent
For your dates
$82 USD
Quality Inn near Medical CenterHotel
Rochester (MN), United States
Quality Inn near Medical Center
★★★
7.8Very Good
For your dates
$76 USD
Baymont by Wyndham Rochester Mayo Clinic AreaHotel
Rochester (MN), United States
Baymont by Wyndham Rochester Mayo Clinic Area
★★★
7.8Very Good
For your dates
$73 USD
Extended Stay America Suites - Rochester - NorthHotel
Rochester (MN), United States
Extended Stay America Suites - Rochester - North
★★★
7.8Very Good
For your dates
$72 USD
Red Carpet Inn RochesterHotel
Rochester (MN), United States
Red Carpet Inn Rochester
★★
7.4Very Good
For your dates
$60 USD
Super 8 By Wyndham Rochester Mayo Clinic AreaHotel
Rochester (MN), United States
Super 8 By Wyndham Rochester Mayo Clinic Area
★★
7.3Very Good
For your dates
$58 USD
MainStay Suites Rochester South Mayo ClinicHotel
Rochester (MN), United States
MainStay Suites Rochester South Mayo Clinic
★★
8.0Excellent
For your dates
$57 USD
Microtel Inn & Suites by Wyndham Rochester North Mayo ClinicHotel
Rochester (MN), United States
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
★★
8.2Excellent
For your dates
$55 USD
Motel 6 Rochester, MNHotel
Rochester (MN), United States
Motel 6 Rochester, MN
★★
4.9Good
For your dates
$55 USD
Towers at the Kahler GrandHotel
Rochester (MN), United States
Towers at the Kahler Grand
★★★★
9.7Exceptional
Aspen Suites - RochesterHotel
Rochester (MN), United States
Aspen Suites - Rochester
★★★
7.6Very Good
Hotel Rochester, MNHotel
Rochester (MN), United States
Hotel Rochester, MN
★★★
5.9Good
Econo Lodge Mayo Clinic AreaHotel
Rochester (MN), United States
Econo Lodge Mayo Clinic Area
★★★★★
0.0Good

The Best Rochester (MN) Staycation Hotels

Whether you’re planning a weekend staycation in Rochester (MN) or a longer escape acrossUnited States, Staycation curates the finest places to stay — from boutique hideaways and heritage hotels to iconic luxury properties. Every Rochester (MN) staycation hotel is ranked by real guest scores, so you can book with confidence.

Rates are powered by Agoda, with live availability and competitive pricing. Pick your dates above to see tonight’s best Rochester (MN) staycation deals, or explore other destinations in North America.