Santa Cruz De La Sierra staycation hotels

South America · Bolivia

Your Santa Cruz De La Sierra Staycation

Hand-picked hotels in Santa Cruz De La Sierra — ranked by real guest scores, with live Agoda rates and one-tap booking. From boutique hideaways to luxury icons, every stay is curated by Staycation.

19
Curated stays
8.2/ 10
Average guest score
8
5-star properties

19 properties · curated by Staycation

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelHotel
Santa Cruz De La Sierra, Bolivia
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
★★★★
9.1Exceptional
For your dates
$212 USD
Hotel Camino RealHotel
Santa Cruz De La Sierra, Bolivia
Hotel Camino Real
★★★★★
9.3Exceptional
For your dates
$152 USD
Novotel Santa Cruz de la SierraHotel
Santa Cruz De La Sierra, Bolivia
Novotel Santa Cruz de la Sierra
★★★★★
0.0Good
For your dates
$122 USD
Sun HotelHotel
Santa Cruz De La Sierra, Bolivia
Sun Hotel
★★★★★
7.7Very Good
For your dates
$98 USD
ibis Santa Cruz de la SierraHotel
Santa Cruz De La Sierra, Bolivia
ibis Santa Cruz de la Sierra
★★★★
8.8Excellent
For your dates
$90 USD
Hotel CortezHotel
Santa Cruz De La Sierra, Bolivia
Hotel Cortez
★★★★★
9.0Exceptional
For your dates
$88 USD
Hampton by Hilton Santa Cruz/EquipetrolHotel
Santa Cruz De La Sierra, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol
★★★
9.7Exceptional
For your dates
$83 USD
TRYP by Wyndham Santa CruzHotel
Santa Cruz De La Sierra, Bolivia
TRYP by Wyndham Santa Cruz
★★★★
9.3Exceptional
For your dates
$78 USD
HOTEL OSHOHotel
Santa Cruz De La Sierra, Bolivia
HOTEL OSHO
★★★★
8.7Excellent
For your dates
$60 USD
Delfines Collection Hotel by MercureHotel
Santa Cruz De La Sierra, Bolivia
Delfines Collection Hotel by Mercure
★★★★
6.0Good
For your dates
$58 USD
Marriott Santa Cruz de la Sierra HotelHotel
Santa Cruz De La Sierra, Bolivia
Marriott Santa Cruz de la Sierra Hotel
★★★★★
8.9Excellent
Swissôtel Santa Cruz De La SierraHotel
Santa Cruz De La Sierra, Bolivia
Swissôtel Santa Cruz De La Sierra
★★★★★
8.4Excellent
Terranova SuitesHotel
Santa Cruz De La Sierra, Bolivia
Terranova Suites
★★★★★
8.1Excellent
Buganvillas Hotel Suites & SpaHotel
Santa Cruz De La Sierra, Bolivia
Buganvillas Hotel Suites & Spa
★★★★★
8.0Excellent
Hotel LP Santa Cruz CentroHotel
Santa Cruz De La Sierra, Bolivia
Hotel LP Santa Cruz Centro
★★★
7.7Very Good
Hotel ArenalHotel
Santa Cruz De La Sierra, Bolivia
Hotel Arenal
★★★★
6.2Good
Hotel Puerta Del ReyHotel
Santa Cruz De La Sierra, Bolivia
Hotel Puerta Del Rey
★★★★
6.0Good
Hotel Las AméricasHotel
Santa Cruz De La Sierra, Bolivia
Hotel Las Américas
★★★
0.0Good
Torre Hotel EjecutivoHotel
Santa Cruz De La Sierra, Bolivia
Torre Hotel Ejecutivo
★★★★
0.0Good

The Best Santa Cruz De La Sierra Staycation Hotels

Whether you’re planning a weekend staycation in Santa Cruz De La Sierra or a longer escape acrossBolivia, Staycation curates the finest places to stay — from boutique hideaways and heritage hotels to iconic luxury properties. Every Santa Cruz De La Sierra staycation hotel is ranked by real guest scores, so you can book with confidence.

Rates are powered by Agoda, with live availability and competitive pricing. Pick your dates above to see tonight’s best Santa Cruz De La Sierra staycation deals, or explore other destinations in South America.