Syracuse staycation hotels

Europe · Italy

Your Syracuse Staycation

Hand-picked hotels in Syracuse — ranked by real guest scores, with live Agoda rates and one-tap booking. From boutique hideaways to luxury icons, every stay is curated by Staycation.

43
Curated stays
8.2/ 10
Average guest score
7
5-star properties

43 properties · curated by Staycation

Grand Hotel Des ÉtrangersHotel
Syracuse, Italy
Grand Hotel Des Étrangers
★★★★★
8.7Excellent
For your dates
$1,697 USD
MinaretoHotel
Syracuse, Italy
Minareto
★★★★★
8.9Excellent
For your dates
$798 USD
Algila Ortigia Charme HotelHotel
Syracuse, Italy
Algila Ortigia Charme Hotel
★★★★
9.4Exceptional
For your dates
$514 USD
Dimora Caiammari Luxury Hotel & SpaHotel
Syracuse, Italy
Dimora Caiammari Luxury Hotel & Spa
★★★★★
9.4Exceptional
For your dates
$338 USD
Grand Hotel OrtigiaHotel
Syracuse, Italy
Grand Hotel Ortigia
★★★★★
9.0Exceptional
For your dates
$337 USD
Hotel VillamareHotel
Syracuse, Italy
Hotel Villamare
★★★★
3.6Good
For your dates
$287 USD
Grand Hotel Villa PolitiHotel
Syracuse, Italy
Grand Hotel Villa Politi
★★★★
8.3Excellent
For your dates
$279 USD
Hotel Bulla RegiaHotel
Syracuse, Italy
Hotel Bulla Regia
★★★
6.3Good
For your dates
$279 USD
Domus Mariae BenessereHotel
Syracuse, Italy
Domus Mariae Benessere
★★★★
8.9Excellent
For your dates
$277 USD
Domus Mariae AlbergoHotel
Syracuse, Italy
Domus Mariae Albergo
★★★
9.9Exceptional
For your dates
$269 USD
Hotel RelaxHotel
Syracuse, Italy
Hotel Relax
★★★★
8.1Excellent
For your dates
$260 USD
Hotel GargalloHotel
Syracuse, Italy
Hotel Gargallo
★★★
8.7Excellent
For your dates
$230 USD
Eureka Palace Hotel Spa ResortHotel
Syracuse, Italy
Eureka Palace Hotel Spa Resort
★★★★
0.0Good
For your dates
$213 USD
Life Hotels Kalaonda ResortHotel
Syracuse, Italy
Life Hotels Kalaonda Resort
★★★★
7.5Very Good
For your dates
$205 USD
Albatros HotelHotel
Syracuse, Italy
Albatros Hotel
★★★★
7.8Very Good
For your dates
$143 USD
Hotel Villa FanusaHotel
Syracuse, Italy
Hotel Villa Fanusa
★★★★
6.9Good
For your dates
$128 USD
Dolce by Wyndham Siracusa I Monasteri Golf & SpaHotel
Syracuse, Italy
Dolce by Wyndham Siracusa I Monasteri Golf & Spa
★★★★★
8.2Excellent
For your dates
$111 USD
Residence dei BaroniHotel
Syracuse, Italy
Residence dei Baroni
★★★★
8.7Excellent
For your dates
$104 USD
Panorama HotelHotel
Syracuse, Italy
Panorama Hotel
★★★★
7.2Very Good
For your dates
$104 USD
Alla GiudeccaHotel
Syracuse, Italy
Alla Giudecca
★★★
8.7Excellent
For your dates
$97 USD
Palazzo Artemide - VRetreats, SLH CollectionHotel
Syracuse, Italy
Palazzo Artemide - VRetreats, SLH Collection
9.6Exceptional
Caportigia Boutique HotelHotel
Syracuse, Italy
Caportigia Boutique Hotel
★★★★★
9.4Exceptional
Elsa d'Ortigia - I Tre ArchiHotel
Syracuse, Italy
Elsa d'Ortigia - I Tre Archi
9.3Exceptional
Livingston HotelHotel
Syracuse, Italy
Livingston Hotel
★★★★
9.2Exceptional
Hotel PostaHotel
Syracuse, Italy
Hotel Posta
★★★
9.2Exceptional
Ortea Palace Hotel, Sicily, Autograph CollectionHotel
Syracuse, Italy
Ortea Palace Hotel, Sicily, Autograph Collection
★★★★★
9.1Exceptional
hotel CentraleHotel
Syracuse, Italy
hotel Centrale
★★★★
8.9Excellent
Hotel Borgo PantanoHotel
Syracuse, Italy
Hotel Borgo Pantano
★★★★
8.9Excellent
Hotel Casa MiaHotel
Syracuse, Italy
Hotel Casa Mia
★★★
8.7Excellent
Mercure Siracusa PrometeoHotel
Syracuse, Italy
Mercure Siracusa Prometeo
★★★★
8.6Excellent
Grande Albergo AlfeoHotel
Syracuse, Italy
Grande Albergo Alfeo
8.3Excellent
Hotel SbarcaderoHotel
Syracuse, Italy
Hotel Sbarcadero
★★★
8.3Excellent
Hotel MediterraneoHotel
Syracuse, Italy
Hotel Mediterraneo
★★★
7.9Very Good
UNA Hotels One Siracusa Wellness & SPAHotel
Syracuse, Italy
UNA Hotels One Siracusa Wellness & SPA
★★★★
7.9Very Good
Hotel ComoHotel
Syracuse, Italy
Hotel Como
★★★
7.6Very Good
Hotel dei ColonialiHotel
Syracuse, Italy
Hotel dei Coloniali
★★★
7.4Very Good
Valle di Mare Country ResortHotel
Syracuse, Italy
Valle di Mare Country Resort
★★★★
7.3Very Good
Hotel Archimede OrtigiaHotel
Syracuse, Italy
Hotel Archimede Ortigia
★★★
7.2Very Good
Charme Hotel Villa Principe FitaliaHotel
Syracuse, Italy
Charme Hotel Villa Principe Fitalia
★★★★
7.2Very Good
Hotel Scala GrecaHotel
Syracuse, Italy
Hotel Scala Greca
★★★
4.3Good
Hotel Como SiracusaHotel
Syracuse, Italy
Hotel Como Siracusa
★★★
0.0Good
Musciara Siracusa ResortHotel
Syracuse, Italy
Musciara Siracusa Resort
★★★
0.0Good
Villa Dei PapiriHotel
Syracuse, Italy
Villa Dei Papiri
★★★
0.0Good

The Best Syracuse Staycation Hotels

Whether you’re planning a weekend staycation in Syracuse or a longer escape acrossItaly, Staycation curates the finest places to stay — from boutique hideaways and heritage hotels to iconic luxury properties. Every Syracuse staycation hotel is ranked by real guest scores, so you can book with confidence.

Rates are powered by Agoda, with live availability and competitive pricing. Pick your dates above to see tonight’s best Syracuse staycation deals, or explore other destinations in Europe.