Central America and Caribbean · Panama
Panama Staycation
The highest-rated hotels across Panama — from boutique city hideaways to landmark luxury resorts. Every stay is hand-picked by Staycation and ranked by real guest scores, with live Agoda rates and one-tap booking.
137
Hotels listed
9.1/ 10
Top picks’ avg score
22
5-star properties
Where to Stay
Top Cities in Panama
Panama City
Panama · 78 hotels
Bocas del Toro
Panama · 13 hotels
Boquete
Panama · 9 hotels
David
Panama · 8 hotels
Tocumen
Panama · 4 hotels
Las Escobas del Venado
Panama · 3 hotels
Los Naranjos
Panama · 2 hotels
Gamboa
Panama · 2 hotels
Bastimentos
Panama · 2 hotels
El Chirú
Panama · 1 hotel
Isla Cristobal
Panama · 1 hotel
El Pajonal
Panama · 1 hotel
Curated by Staycation
Top Panama Staycation Hotels
HotelPanama City, Panama
Hotel Plaza Herrera
★★★★
HotelPanama City, Panama
Sofitel Legend Casco Viejo
★★★★★
HotelPanama City, Panama
JW Marriott Panama
★★★★★
HotelPanama City, Panama
Intercontinental Miramar Panama By IHG
★★★★
HotelPanama City, Panama
Waldorf Astoria Panama
★★★★★
HotelPanama City, Panama
Hilton Panama
★★★★
HotelEl Valle De Anton, Panama
Hotel La Compania Del Valle
★★★★★
HotelPanama City, Panama
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City
★★★★★
HotelPanama City, Panama
W Panama
★★★★★
HotelPanama City, Panama
The Westin Panama
★★★★
HotelPanama City, Panama
Sortis Hotel, Spa & Casino, Autograph Collection
★★★★★
HotelEl Chirú, Panama
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
★★★★★
The Best Panama Staycation Hotels
Whether you’re planning a weekend staycation or a longer escape across Panama, Staycation curates the finest places to stay — from boutique hideaways and heritage hotels to iconic luxury properties. Every hotel is ranked by real guest scores, so you can book with confidence.
Rates are powered by Agoda, with live availability and competitive pricing. Start in Panama City, Bocas del Toro or Boquete, or explore every Panama destination.